nitromethylene; neonicotinoid

NOMENCLATURE
Common name clothianidin (BSI, pa ISO)
IUPAC name (E)-1-(2-chloro-1,3-thiazol-5-ylmethyl)-3-methyl-2-nitroguanidine
Chemical Abstracts name (E)-N-[(2-chloro-5-thiazolyl)methyl]-N'-methyl-N''-nitroguanidine
CAS RN [210880-92-5]; (formerly [205510-53-8]) Development codes TI-435 (Takeda); V-10066

PHYSICAL CHEMISTRY
Mol. wt. 249.7 M.f. C6H8ClN5O2S

COMMERCIALISATION
History Discovered by Takeda Chemical Industries and under development jointly with Bayer AG. Manufacturers Takeda

APPLICATIONS
Biochemistry Agonist of the nicotinic acetylcholine receptor, affecting the synapses in the insect central nervous system. Uses Soil, foliar and seed insecticide, under development for control of sucking and chewing insects in rice, fruit and vegetables.